Publications

198) Discovery of drug targets and therapeutic agents based on drug repositioning to treat lung adenocarcinoma

Graves OK, Kim W, Özcan M, Ashraf S, Turkez H, Yuan M, Zhang C, Mardinoglu A, Li X.

Biomed Pharmacother. 2023 Mar 10;161:114486.

197) Cardiomyocyte-specific PCSK9 deficiency compromises mitochondrial bioenergetics and heart function

Laudette M, Lindbom M, Arif M, Cinato M, Ruiz M, Doran S, Miljanovic A, Rutberg M, Andersson L, Klevstig M, Henricsson M, Bergh PO, Bollano E, Aung N, Smith JG, Pilon M, Hyötyläinen T, Orešič M, Perkins R, Mardinoglu A, Levin MC, Borén J.

Cardiovasc Res. 2023 Mar 6:cvad041.

196) Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection

Mikaeloff F, Gelpi M, Benfeitas R, Knudsen AD, Vestad B, Høgh J, Hov JR, Benfield T, Murray D, Giske CG, Mardinoglu A, Trøseid M, Nielsen SD, Neogi U.

Elife. 2023 Feb 16;12:e82785.

195) Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase

Battisti UM, Gao C, Akladios F, Kim W, Yang H, Bayram C, Bolat I, Kiliclioglu M, Yuksel N, Tozlu OO, Zhang C, Sebhaoui J, Iqbal S, Shoaie S, Hacimuftuoglu A, Yildirim S, Turkez H, Uhlen M, Boren J, Mardinoglu A, Grøtli M.

Nutrients. 2023 Jan 22;15(3):577.

194) Combined metabolic activators improve cognitive functions in Alzheimer’s disease patients: a randomised, double-blinded, placebo-controlled phase-II trial

Yulug B, Altay O, Li X, Hanoglu L, Cankaya S, Lam S, Velioglu HA, Yang H, Coskun E, Idil E, Nogaylar R, Ozsimsek A, Bayram C, Bolat I, Oner S, Tozlu OO, Arslan ME, Hacimuftuoglu A, Yildirim S, Arif M, Shoaie S, Zhang C, Nielsen J, Turkez H, Borén J, Uhlén M, Mardinoglu A.

Transl Neurodegener. 2023 Jan 26;12(1):4.

193) Lipoic Acid Conjugated Boron Hybrids Enhance Wound Healing and Antimicrobial Processes

Türkez H, Yıldırım ÖÇ, Öner S, Kadı A, Mete A, Arslan ME, Şahin İO, Yapça ÖE, Mardinoğlu A.

Pharmaceutics. 2022 Dec 31;15(1):149.

192) Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases

Turkez H, Altay O, Yildirim S, Li X, Yang H, Bayram C, Bolat I, Oner S, Tozlu OO, Arslan ME, Arif M, Yulug B, Hanoglu L, Cankaya S, Lam S, Velioglu HA, Coskun E, Idil E, Nogaylar R, Ozsimsek A, Hacimuftuoglu A, Shoaie S, Zhang C, Nielsen J, Borén J, Uhlén M, Mardinoglu A.

Life Sci. 2023 Feb 1;314:121325.

191) In Vitro Transcriptome Analysis of Cobalt Boride Nanoparticles on Human Pulmonary Alveolar Cells

Arslan ME, Tatar A, Yıldırım ÖÇ, Şahin İO, Ozdemir O, Sonmez E, Hacımuftuoglu A, Acikyildiz M, Geyikoğlu F, Mardinoğlu A, Türkez H.

Materials (Basel). 2022 Dec 6;15(23):8683.

190) Toxicity of Glycyl-l-Prolyl-l-Glutamate Pseudotripeptides: Cytotoxic, Oxidative, Genotoxic, and Embryotoxic Perspectives

Turkez H, Ozdemir Tozlu O, Tatar A, Arslan ME, Cadirci K, Marinelli L, Yapca OE, Cacciatore I, Di Stefano A, Mardinoglu A.

J Toxicol. 2022 Nov 19;2022:3775194.

189) Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase

Battisti UM, Gao C, Nilsson O, Akladios F, Lulla A, Bogucka A, Nain-Perez A, Håversen L, Kim W, Boren J, Hyvönen M, Uhlen M, Mardinoglu A, Grøtli M.

Chembiochem. 2023 Jan 3;24(1):e202200339.

188) Editorial: Application of systems biology in molecular characterization and diagnosis of cancer, Volume II

Wei Y, Zhang C, Mardinoglu A, Zhang P.

Front Mol Biosci. 2022 Nov 25;9:1089463.

187) In Vitro and In Vivo Neuroprotective Effects of Sarcosine

Tanas A, Tozlu ÖÖ, Gezmiş T, Hacimüftüoğlu A, Abd El-Aty AM, Ceylan O, Mardinoğlu A, Türkez H.

Biomed Res Int. 2022 Oct 15;2022:5467498.

186) Assessment of the neuroprotective potential of d-cycloserine and l-serine in aluminum chloride-induced experimental models of Alzheimer’s disease: In vivo and in vitro studies

Tozlu, Ö. Ö., Türkez, H., Okkay, U., Ceylan, O., Bayram, C., Hacımüftüoğlu, A., & Mardinoğlu, A.

Front Nutr. 2022 Sep 8;9:981889.

185) Boron Compounds Exhibit Protective Effects against Aluminum-Induced Neurotoxicity and Genotoxicity: In Vitro and In Vivo Study

Turkez, H., Yildirim, S., Sahin, E., Arslan, M. E., Emsen, B., Tozlu, O. O., Alak, G., Ucar, A., Tatar, A., Hacimuftuoglu, A., Keles, M. S., Geyikoglu, F., Atamanalp, M., Saruhan, F. and Mardinoglu, A.

Toxics. 2022 Jul 28;10(8).

184) Ameliorative Effects by Hexagonal Boron Nitride Nanoparticles against Beta Amyloid Induced Neurotoxicity

Aydin, N., Turkez, H., Tozlu, O. O., Arslan, M. E., Yavuz, M., Sonmez, E., Ozpolat, O. F., Cacciatore, I., Di Stefano, A. and Mardinoglu, A.

Nanomaterials (Basel). 2022 Aug 5;12(15).

183) Boron Nitride Nanoparticles Loaded with a Boron-Based Hybrid as a Promising Drug Carrier System for Alzheimer’s Disease Treatment

Yildirim, O. C., Arslan, M. E., Oner, S., Cacciatore, I., Di Stefano, A., Mardinoglu, A. and Turkez, H.

Int J Mol Sci. 2022 Jul 26;23(15).

182) Molecular Genetics and Cytotoxic Responses to Titanium Diboride and Zinc Borate Nanoparticles on Cultured Human Primary Alveolar Epithelial Cells

Turkez, H., Arslan, M. E., Tatar, A., Ozdemir, O., Sonmez, E., Cadirci, K., Hacimuftuoglu, A., Ceylan, B., Acikyildiz, M., Kahraman, C. Y., Geyikoglu, F., Tatar, A. and Mardinoglu, A.

Materials (Basel). 2022 Mar 22;15(7).

181) A Gene Co-Expression Network-Based Drug Repositioning Approach Identifies Candidates for Treatment of Hepatocellular Carcinoma

Yuan, M., Shong, K., Li, X., Ashraf, S., Shi, M., Kim, W., Nielsen, J., Turkez, H., Shoaie, S., Uhlen, M., Zhang, C. and Mardinoglu, A.

Cancers (Basel). 2022 Mar 19;14(6).

180) Development of l-Dopa-containing diketopiperazines as blood-brain barrier shuttle

Cornacchia, C., Marinelli, L., Di Rienzo, A., Dimmito, M. P., Serra, F., Di Biase, G., De Filippis, B., Turkez, H., Mardinoglu, A., Bellezza, I., Di Stefano, A. and Cacciatore, I.

Eur J Med Chem. 2022 Sep 8;243:114746.

179) BMP4 and Gremlin 1 regulate hepatic cell senescence during clinical progression of NAFLD/NASH

Baboota, R. K., Rawshani, A., Bonnet, L., Li, X., Yang, H., Mardinoglu, A., Tchkonia, T., Kirkland, J. L., Hoffmann, A., Dietrich, A., Boucher, J., Bluher, M. and Smith, U.

Nat Metab. 2022 Aug;4(8):1007-1021.

178) Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning

Zhang, C., Shi, M., Kim, W., Arif, M., Klevstig, M., Li, X., Yang, H., Bayram, C., Bolat, I., Tozlu, O. O., Hacimuftuoglu, A., Yildirim, S., Sebhaoui, J., Iqbal, S., Wei, Y., Shi, X., Nielsen, J., Turkez, H., Uhlen, M., Boren, J. and Mardinoglu, A.

EBioMedicine. 2022 Sep;83:104214.

177) Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity

Ambikan, A. T., Yang, H., Krishnan, S., Svensson Akusjarvi, S., Gupta, S., Lourda, M., Sperk, M., Arif, M., Zhang, C., Nordqvist, H., Ponnan, S. M., Sonnerborg, A., Treutiger, C. J., O’Mahony, L., Mardinoglu, A., Benfeitas, R. and Neogi, U.

Cell Syst. 2022 Aug 17;13(8):665-681.e4.

176) Author Correction: Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

Mahdessian, D., Cesnik, A. J., Gnann, C., Danielsson, F., Stenstrom, L., Arif, M., Zhang, C., Le, T., Johansson, F., Schutten, R., Backstrom, A., Axelsson, U., Thul, P., Cho, N. H., Carja, O., Uhlen, M., Mardinoglu, A., Stadler, C., Lindskog, C., Ayoglu, B., Leonetti, M. D., Ponten, F., Sullivan, D. P. and Lundberg, E.

Nature. 2022 Aug;608(7924):E32.

175) Chronic hyperinsulinemia promotes human hepatocyte senescence

Baboota, R. K., Spinelli, R., Erlandsson, M. C., Brandao, B. B., Lino, M., Yang, H., Mardinoglu, A., Bokarewa, M. I., Boucher, J., Kahn, C. R. and Smith, U.

Mol Metab. 2022 Oct;64:101558.

174) MRI characterization of skeletal muscle size and fatty infiltration in long-term trained and untrained individuals

Emanuelsson, E. B., Berry, D. B., Reitzner, S. M., Arif, M., Mardinoglu, A., Gustafsson, T., Ward, S. R., Sundberg, C. J. and Chapman, M. A.

Physiol Rep. 2022 Jul;10(14):e15398.

173) Repositioning of Anti-Inflammatory Drugs for the Treatment of Cervical Cancer Sub-Types

Kori, M., Arga, K. Y., Mardinoglu, A. and Turanli, B.

Front Pharmacol. 2022 Jun 13;13:884548.

172) Genome-scale metabolic modelling of the human gut microbiome reveals changes in the glyoxylate and dicarboxylate metabolism in metabolic disorders

Proffitt, C., Bidkhori, G., Lee, S., Tebani, A., Mardinoglu, A., Uhlen, M., Moyes, D. L. and Shoaie, S.

iScience. 2022 Jun 2;25(7):104513.

171) Machine Learning Analysis Reveals Biomarkers for the Detection of Neurological Diseases

Lam, S., Arif, M., Song, X., Uhlen, M. and Mardinoglu, A.

Front Mol Neurosci. 2022 May 31;15:889728.

170) Recent Progress and Future Direction for the Application of Multiomics Data in Clinical Liver Transplantation

Liu, Z., Xu, J., Que, S., Geng, L., Zhou, L., Mardinoglu, A. and Zheng, S.

J Clin Transl Hepatol. 2022 Apr 28;10(2):363-373.

169) Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach

Li, X., Shong, K., Kim, W., Yuan, M., Yang, H., Sato, Y., Kume, H., Ogawa, S., Turkez, H., Shoaie, S., Boren, J., Nielsen, J., Uhlen, M., Zhang, C. and Mardinoglu, A.

EBioMedicine. 2022 Apr;78:103963.

168) Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase

Nain-Perez, A., Foller Fuchtbauer, A., Haversen, L., Lulla, A., Gao, C., Matic, J., Monjas, L., Rodriguez, A., Brear, P., Kim, W., Hyvonen, M., Boren, J., Mardinoglu, A., Uhlen, M. and Grotli, M.

Eur J Med Chem. 2022 Apr 15;234:114270.

167) Stratification of the Gut Microbiota Composition Landscape across the Alzheimer’s Disease Continuum in a Turkish Cohort

Yildirim, S., Nalbantoglu, O. U., Bayraktar, A., Ercan, F. B., Gundogdu, A., Velioglu, H. A., Gol, M. F., Soylu, A. E., Koc, F., Gulpinar, E. A., Kadak, K. S., Arikan, M., Mardinoglu, A., Kocak, M., Koseoglu, E. and Hanoglu, L.

mSystems. 2022 Feb 22;7(1):e0000422.

166) Multiomics Analysis Reveals the Impact of Microbiota on Host Metabolism in Hepatic Steatosis

Zeybel, M., Arif, M., Li, X., Altay, O., Yang, H., Shi, M., Akyildiz, M., Saglam, B., Gonenli, M. G., Yigit, B., Ulukan, B., Ural, D., Shoaie, S., Turkez, H., Nielsen, J., Zhang, C., Uhlen, M., Boren, J. and Mardinoglu, A.

Adv Sci (Weinh). 2022 Apr;9(11):e2104373.

165) Correction to: Toxicogenomics directory of chemically exposed human hepatocytes

Grinberg, M., Stober, R. M., Edlund, K., Rempel, E., Godoy, P., Reif, R., Widera, A., Madjar, K., Schmidt-Heck, W., Marchan, R., Sachinidis, A., Spitkovsky, D., Hescheler, J., Carmo, H., Arbo, M. D., van de Water, B., Wink, S., Vinken, M., Rogiers, V., Escher, S., Hardy, B., Mitic, D., Apic, G., Myatt, G., Waldmann, T., Mardinoglu, A., Damm, G., Seehofer, D., Nussler, A., Weiss, T. S., Oberemm, A., Lampen, A., Schaap, M. M., Luijten, M., van Steeg, H., Thasler, W. E., Kleinjans, J. C. S., Stierum, R. H., Leist, M., Rahnenfuhrer, J. and Hengstler, J. G.

Arch Toxicol. 2022 Mar;96(3):945-946.

164) Genome-wide annotation of protein-coding genes in pig

Karlsson, M., Sjostedt, E., Oksvold, P., Sivertsson, A., Huang, J., Alvez, M. B., Arif, M., Li, X., Lin, L., Yu, J., Ma, T., Xu, F., Han, P., Jiang, H., Mardinoglu, A., Zhang, C., von Feilitzen, K., Xu, X., Wang, J., Yang, H., Bolund, L., Zhong, W., Fagerberg, L., Lindskog, C., Ponten, F., Mulder, J., Luo, Y. and Uhlen, M.

BMC Biol. 2022 Jan 25;20(1):25.

163) Improvement of the performance of anticancer peptides using a drug repositioning pipeline

Mohammadi, E., Tahmoorespur, M., Benfeitas, R., Altay, O., Javadmanesh, A., Lam, S., Mardinoglu, A. and Sekhavati, M. H.

Biotechnol J. 2022 Jan;17(1):e2100417.

162) Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties

Cacciatore, I., H. Turkez, A. Di Rienzo, M. Ciulla, A. Mardinoglu, and A. Di Stefano

RSC Med Chem 12, no. 11 (Nov 17 2021): 1944-49.

161) Combined Metabolic Activators Therapy Ameliorates Liver Fat in Nonalcoholic Fatty Liver Disease Patients

Zeybel, M., O. Altay, M. Arif, X. Li, H. Yang, C. Fredolini, M. Akyildiz, B. Saglam, M. G. Gonenli, D. Ural, W. Kim, J. M. Schwenk, C. Zhang, S. Shoaie, J. Nielsen, M. Uhlen, J. Boren, and A. Mardinoglu

Mol Syst Biol 17, no. 10 (Oct 2021): e10459.

160) Revealing the Molecular Mechanisms of Alzheimer’s Disease Based on Network Analysis

Bayraktar, A., S. Lam, O. Altay, X. Li, M. Yuan, C. Zhang, M. Arif, H. Turkez, M. Uhlen, S. Shoaie, and A. Mardinoglu

Int J Mol Sci 22, no. 21 (Oct 26 2021).

159) The Assessment of Selected Mirna Profile in Familial Mediterranean Fever

Kahraman, C. Y., M. E. Egin, A. Tatar, H. Turkez, and A. Mardinoglu

Biomed Res Int 2021 (2021): 6495700.

158) Systems Biology Approaches to Decipher the Underlying Molecular Mechanisms of Glioblastoma Multiforme

Kaynar, A., O. Altay, X. Li, C. Zhang, H. Turkez, M. Uhlen, S. Shoaie, and A. Mardinoglu

Int J Mol Sci 22, no. 24 (Dec 8 2021).

157) Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer’s and Parkinson’s Diseases

Lam, S., N. Hartmann, R. Benfeitas, C. Zhang, M. Arif, H. Turkez, M. Uhlen, C. Englert, R. Knight, and A. Mardinoglu

Biomedicines 9, no. 10 (Sep 24 2021).

156) Therapeutic Potential of Ferulic Acid in Alzheimer’s Disease

Turkez, H., M. E. Arslan, J. N. Barboza, C. Y. Kahraman, D. P. de Sousa, and A. Mardinoglu

Curr Drug Deliv (Dec 28 2021).

155) In Vitro Transcriptome Response to Propolis in Differentiated Sh-Sy5y Neurons

Turkez, H., M. E. Arslan, A. Yilmaz, F. Doru, O. Caglar, E. Arslan, A. Tatar, A. Hacimuftuoglu, A. M. Abd El-Aty, and A. Mardinoglu

J Food Biochem 45, no. 12 (Dec 2021): e13990.

154) Next Generation Plasma Proteome Profiling of Covid-19 Patients with Mild to Moderate Symptoms

Zhong, W., O. Altay, M. Arif, F. Edfors, L. Doganay, A. Mardinoglu, M. Uhlen, and L. Fagerberg

EBioMedicine 74 (Dec 2021): 103723.

153) A network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic fatty liver disease

Yang H, Arif M, Yuan M, Li X, Shong K, Türkez H, Nielsen J, Uhlén M, Borén J, Zhang C, Mardinoglu A.

iScience. 103222.

152) Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in Hamsters Fed with a High-Fat Diet

Yang H, Mayneris-Perxachs J, Boqué N, del Bas JM, Arola L, Yuan M, Turkez H, Uhlen M, Boren J, Zhang C, Mardinoglu A, Caimari, A.

Biomedicines, 9(10), 1440

151) Combined Metabolic Activators Improve Cognitive Functions without Altering Motor Scores in Parkinson’s Disease

Yulug, Burak, Ozlem Altay, Xiangyu Li, Lutfu Hanoglu, Seyda Cankaya, Simon Lam, Hong Yang, Ebru Coskun, Ezgi İdil, Rahim Nogaylar, Ahmet Hacımuftuoglu, Muhammad. Arif, Saeed Shoaie, Cheng Zhang, Jens Nielsen, Hasan Turkez, Jan Borén, Mathias Uhlén, and Adil Mardinoglu.

medRxiv

150) Combined Metabolic Activators Improves Cognitive Functions in Alzheimer’s Disease

Yulug, Burak, Ozlem Altay, Xiangyu Li, Lutfu Hanoglu, Seyda Cankaya, Simon Lam, Hong Yang, Ebru Coskun, Ezgi İdil, Rahim Nogaylar, Cemil Bayram, Ismail Bolat, Sena Oner, Ozlem Ozdemir Tozlu, Mehmet Enes Arslan, Ahmet Hacımuftuoglu, Serkan Yildirim, Muhammad. Arif, Saeed Shoaie, Cheng Zhang, Jens Nielsen, Hasan Turkez, Jan Borén, Mathias Uhlén, and Adil Mardinoglu.

Preprint

149) Systems biology based drug repositioning for development of cancer therapy

Turanli, B., O. Altay, J. Boren, H. Turkez, J. Nielsen, M. Uhlen, K. Y. Arga, and A. Mardinoglu

Semin Cancer Biol, 68: 47-58.

148) A single-cell type transcriptomics map of human tissues

Karlsson, M., C. Zhang, L. Mear, W. Zhong, A. Digre, B. Katona, E. Sjostedt, L. Butler, J. Odeberg, P. Dusart, F. Edfors, P. Oksvold, K. von Feilitzen, M. Zwahlen, M. Arif, O. Altay, X. Li, M. Ozcan, A. Mardinoglu, L. Fagerberg, J. Mulder, Y. Luo, F. Ponten, M. Uhlen, and C. Lindskog

Sci Adv, 7.

147) Acute kidney injury leading to CKD is associated with a persistence of metabolic dysfunction and hypertriglyceridemia

Harzandi, A., S. Lee, G. Bidkhori, S. Saha, B. M. Hendry, A. Mardinoglu, S. Shoaie, and C. C. Sharpe

iScience, 24: 102046.

146) Addressing the heterogeneity in liver diseases using biological networks

Lam, S., S. Doran, H. H. Yuksel, O. Altay, H. Turkez, J. Nielsen, J. Boren, M. Uhlen, and A. Mardinoglu

Brief Bioinform, 22: 1751-66.

145) Anticancer effects of novel NSAIDs derivatives on cultured human glioblastoma cells

Ozdemir, O., L. Marinelli, I. Cacciatore, M. Ciulla, B. Emsen, A. Di Stefano, A. Mardinoglu, and H. Turkez

Z Naturforsch C J Biosci, 76: 329-35.

144) Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19

Altay, O., M. Arif, X. Li, H. Yang, M. Aydin, G. Alkurt, W. Kim, D. Akyol, C. Zhang, G. Dinler-Doganay, H. Turkez, S. Shoaie, J. Nielsen, J. Boren, O. Olmuscelik, L. Doganay, M. Uhlen, and A. Mardinoglu

Adv Sci (Weinh), 8: e2101222.

143) Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers

Li, X., W. Kim, M. Arif, C. Gao, A. Hober, D. Kotol, L. Strandberg, B. Forsstrom, A. Sivertsson, P. Oksvold, H. Turkez, M. Grotli, Y. Sato, H. Kume, S. Ogawa, J. Boren, J. Nielsen, M. Uhlen, C. Zhang, and A. Mardinoglu

Cancers (Basel), 13.

142) Editorial: Application of Systems Biology in Molecular Characterization and Diagnosis of Cancer

Zhang, C., Y. Wei, A. Mardinoglu, and P. Zhang

Front Mol Biosci, 8: 668146.

141) Glucosylceramide synthase deficiency in the heart compromises beta1-adrenergic receptor trafficking

Andersson, L., M. Cinato, I. Mardani, A. Miljanovic, M. Arif, A. Koh, M. Lindbom, M. Laudette, E. Bollano, E. Omerovic, M. Klevstig, M. Henricsson, P. Fogelstrand, K. Sward, M. Ekstrand, M. Levin, J. Wikstrom, S. Doran, T. Hyotylainen, L. Sinisalu, M. Oresic, A. Tivesten, M. Adiels, M. O. Bergo, R. Proia, A. Mardinoglu, A. Jeppsson, J. Boren, and M. C. Levin

Eur Heart J.

140) Glycyl-L-Prolyl-L-Glutamate Pseudotripeptides for Treatment of Alzheimer’s Disease

Turkez, H., I. Cacciatore, L. Marinelli, E. Fornasari, M. E. Aslan, K. Cadirci, C. Y. Kahraman, O. Caglar, A. Tatar, G. Di Biase, A. Hacimuftuoglu, A. Di Stefano, and A. Mardinoglu

Biomolecules, 11.

139) In vitro neuroprotective effects of farnesene sesquiterpene on alzheimer’s disease model of differentiated neuroblastoma cell line

Arslan, M. E., H. Turkez, and A. Mardinoglu

Int J Neurosci, 131: 745-54.

138) iNetModels 2.0: an interactive visualization and database of multi-omics data

Arif, M., C. Zhang, X. Li, C. Gungor, B. Cakmak, M. Arslanturk, A. Tebani, B. Ozcan, O. Subas, W. Zhou, B. Piening, H. Turkez, L. Fagerberg, N. Price, L. Hood, M. Snyder, J. Nielsen, M. Uhlen, and A. Mardinoglu

Nucleic Acids Res, 49: W271-W76.

137) Informing Pharmacokinetic Models With Physiological Data: Oral Population Modeling of L-Serine in Humans

Bosley, J. R., E. Bjornson, C. Zhang, H. Turkez, J. Nielsen, M. Uhlen, J. Boren, and A. Mardinoglu

Front Pharmacol, 12: 643179.

136) Integrative study of diet-induced mouse models of NAFLD identifies PPARalpha as a sexually dimorphic drug target

Smati, S., A. Polizzi, A. Fougerat, S. Ellero-Simatos, Y. Blum, Y. Lippi, M. Regnier, A. Laroyenne, M. Huillet, M. Arif, C. Zhang, F. Lasserre, A. Marrot, T. Al Saati, J. Wan, C. Sommer, C. Naylies, A. Batut, C. Lukowicz, T. Fougeray, B. Tramunt, P. Dubot, L. Smith, J. Bertrand-Michel, N. Hennuyer, J. P. Pradere, B. Staels, R. Burcelin, F. Lenfant, J. F. Arnal, T. Levade, L. Gamet-Payrastre, S. Lagarrigue, N. Loiseau, S. Lotersztajn, C. Postic, W. Wahli, C. Bureau, M. Guillaume, A. Mardinoglu, A. Montagner, P. Gourdy, and H. Guillou

Gut, gutjnl-2020-323323.

135) Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction

Arif, M., M. Klevstig, R. Benfeitas, S. Doran, H. Turkez, M. Uhlen, M. Clausen, J. Wikstrom, D. Etal, C. Zhang, M. Levin, A. Mardinoglu, and J. Boren

Elife, 10.

134) Lysine demethylase LSD1 delivered via small extracellular vesicles promotes gastric cancer cell stemness

Zhao, L. J., Y. Y. Li, Y. T. Zhang, Q. Q. Fan, H. M. Ren, C. Zhang, A. Mardinoglu, W. C. Chen, J. R. Pang, D. D. Shen, J. W. Wang, L. F. Zhao, J. Y. Zhang, Z. Y. Wang, Y. C. Zheng, and H. M. Liu

EMBO Rep, 22: e50922.

133) Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI

van der Kolk, B. W., S. Saari, A. Lovric, M. Arif, M. Alvarez, A. Ko, Z. Miao, N. Sahebekhtiari, M. Muniandy, S. Heinonen, A. Oghabian, R. Jokinen, S. Jukarainen, A. Hakkarainen, J. Lundbom, J. Kuula, P. H. Groop, T. Tukiainen, N. Lundbom, A. Rissanen, J. Kaprio, E. G. Williams, N. Zamboni, A. Mardinoglu, P. Pajukanta, and K. H. Pietilainen

Cell Rep Med, 2: 100226.

132) Multi-omics approaches for revealing the complexity of cardiovascular disease

Doran, S., M. Arif, S. Lam, A. Bayraktar, H. Turkez, M. Uhlen, J. Boren, and A. Mardinoglu

Brief Bioinform, 22.

131) Potential Anticancer Effect of Carvacrol Codrugs on Human Glioblastoma Cells

Yazici, A., L. Marinelli, I. Cacciatore, B. Emsen, P. Eusepi, G. Di Biase, A. Di Stefano, A. Mardinoglu, and H. Turkez

Curr Drug Deliv, 18: 350-56.

130) Promising potential of boron compounds against Glioblastoma: In Vitro antioxidant, anti-inflammatory and anticancer studies

Turkez, H., M. E. Arslan, A. Tatar, and A. Mardinoglu

Neurochem Int, 149: 105137.

129) Revealing the Metabolic Alterations during Biofilm Development of Burkholderia cenocepacia Based on Genome-Scale Metabolic Modeling

Altay, O., C. Zhang, H. Turkez, J. Nielsen, M. Uhlen, and A. Mardinoglu

Metabolites, 11.

128) Safety and Efficacy Assessments to Take Antioxidants in Glioblastoma Therapy: From In Vitro Experiences to Animal and Clinical Studies

Turkez, H., O. O. Tozlu, M. E. Arslan, and A. Mardinoglu

Neurochem Int, 150: 105168.

127) Safety Assessments of Nickel Boride Nanoparticles on the Human Pulmonary Alveolar Cells by Using Cell Viability and Gene Expression Analyses

Turkez, H., M. E. Arslan, E. Sonmez, A. Tatar, F. Geyikoglu, M. Acikyildiz, and A. Mardinoglu

Biol Trace Elem Res, 199: 2602-11.

126) Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey

Alkurt, G., A. Murt, Z. Aydin, O. Tatli, N. B. Agaoglu, A. Irvem, M. Aydin, R. Karaali, M. Gunes, B. Yesilyurt, H. Turkez, A. Mardinoglu, M. Doganay, F. Basinoglu, N. Seyahi, G. Dinler Doganay, and H. L. Doganay

PLoS One, 16: e0247865.

125) Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

Mahdessian, D., A. J. Cesnik, C. Gnann, F. Danielsson, L. Stenstrom, M. Arif, C. Zhang, T. Le, F. Johansson, R. Shutten, A. Backstrom, U. Axelsson, P. Thul, N. H. Cho, O. Carja, M. Uhlen, A. Mardinoglu, C. Stadler, C. Lindskog, B. Ayoglu, M. D. Leonetti, F. Ponten, D. P. Sullivan, and E. Lundberg

Nature, 590: 649-54.

124) Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning

Li, X., W. Kim, K. Juszczak, M. Arif, Y. Sato, H. Kume, S. Ogawa, H. Turkez, J. Boren, J. Nielsen, M. Uhlen, C. Zhang, and A. Mardinoglu

iScience, 24: 102722.

123) Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson’s disease

Rosario, D., G. Bidkhori, S. Lee, J. Bedarf, F. Hildebrand, E. Le Chatelier, M. Uhlen, S. D. Ehrlich, G. Proctor, U. Wullner, A. Mardinoglu, and S. Shoaie

Cell Rep, 34: 108807.

122) Targeted Gene Candidates for Treatment and Early Diagnosis of Age-Related Macular Degeneration

Cinici, E., O. Caglar, M. E. Arslan, N. Dilekmen, B. Utlu, A. Mardinoglu, and H. Turkez

Biomed Res Int, 2021: 6620900.

121) A Resilient Health System in Response to Coronavirus Disease 2019: Experiences of Turkey

Keskinkilic, B., I. Shaikh, A. Tekin, P. Ursu, A. Mardinoglu, and E. A. Mese

Front Public Health, 8: 577021.

120) A systems biology approach for studying neurodegenerative diseases

Lam, S., A. Bayraktar, C. Zhang, H. Turkez, J. Nielsen, J. Boren, S. Shoaie, M. Uhlen, and A. Mardinoglu

Drug Discov Today, 25: 1146-59.

119) Adipose tissue morphology, imaging and metabolomics predicting cardiometabolic risk and family history of type 2 diabetes in non-obese men

Rawshani, A., B. Eliasson, A. Rawshani, J. Henninger, A. Mardinoglu, A. Carlsson, M. Sohlin, M. Ljungberg, A. Hammarstedt, A. Rosengren, and U. Smith

Sci Rep, 10: 9973.

118) An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models

Choi, M. J., S. B. Jung, S. E. Lee, S. G. Kang, J. H. Lee, M. J. Ryu, H. K. Chung, J. Y. Chang, Y. K. Kim, H. J. Hong, H. Kim, H. J. Kim, C. H. Lee, A. Mardinoglu, H. S. Yi, and M. Shong

Diabetologia, 63: 837-52.

117) An atlas of human metabolism

Robinson, J. L., P. Kocabas, H. Wang, P. E. Cholley, D. Cook, A. Nilsson, M. Anton, R. Ferreira, I. Domenzain, V. Billa, A. Limeta, A. Hedin, J. Gustafsson, E. J. Kerkhoven, L. T. Svensson, B. O. Palsson, A. Mardinoglu, L. Hansson, M. Uhlen, and J. Nielsen

Sci Signal, 13.

116) An atlas of the protein-coding genes in the human, pig, and mouse brain

Sjostedt, E., W. Zhong, L. Fagerberg, M. Karlsson, N. Mitsios, C. Adori, P. Oksvold, F. Edfors, A. Limiszewska, F. Hikmet, J. Huang, Y. Du, L. Lin, Z. Dong, L. Yang, X. Liu, H. Jiang, X. Xu, J. Wang, H. Yang, L. Bolund, A. Mardinoglu, C. Zhang, K. von Feilitzen, C. Lindskog, F. Ponten, Y. Luo, T. Hokfelt, M. Uhlen, and J. Mulder

Science, 367.

115) Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning

Mohammadi, E., R. Benfeitas, H. Turkez, J. Boren, J. Nielsen, M. Uhlen, and A. Mardinoglu

Cancers (Basel), 12.

114) Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DM-1 and NKG2D

Sayitoglu, E. C., A. M. Georgoudaki, M. Chrobok, D. Ozkazanc, B. J. Josey, M. Arif, K. Kusser, M. Hartman, T. M. Chinn, R. Potens, C. Pamukcu, R. Krueger, C. Zhang, A. Mardinoglu, E. Alici, H. T. Temple, T. Sutlu, and A. D. Duru

Front Immunol, 11: 40.

113) Classification of clear cell renal cell carcinoma based on PKM alternative splicing

Li, X., B. Turanli, K. Juszczak, W. Kim, M. Arif, Y. Sato, S. Ogawa, H. Turkez, J. Nielsen, J. Boren, M. Uhlen, C. Zhang, and A. Mardinoglu

Heliyon, 6: e03440.

112) Current Status of COVID-19 Therapies and Drug Repositioning Applications

Altay, O., E. Mohammadi, S. Lam, H. Turkez, J. Boren, J. Nielsen, M. Uhlen, and A. Mardinoglu

iScience, 23: 101303.

111) Drug Repositioning for P-Glycoprotein Mediated Co-Expression Networks in Colorectal Cancer

Beklen, H., G. Gulfidan, K. Y. Arga, A. Mardinoglu, and B. Turanli

Front Oncol, 10: 1273.

110) Editorial: Redox Homeostasis and Cancer

Sinha, M., A. Mardinoglu, J. Ghose, and K. Singh

Oxid Med Cell Longev, 2020: 5487381.

109) Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development

Larsson, I., M. Uhlen, C. Zhang, and A. Mardinoglu

Front Genet, 11: 381.

108) Histidyl-Proline Diketopiperazine Isomers as Multipotent Anti-Alzheimer Drug Candidates

Turkez, H., I. Cacciatore, M. E. Arslan, E. Fornasari, L. Marinelli, A. Di Stefano, and A. Mardinoglu

Biomolecules, 10.

107) Improvement in the Current Therapies for Hepatocellular Carcinoma Using a Systems Medicine Approach

Ozcan, M., O. Altay, S. Lam, H. Turkez, Y. Aksoy, J. Nielsen, M. Uhlen, J. Boren, and A. Mardinoglu

Adv Biosyst, 4: e2000030.

106) Integration of molecular profiles in a longitudinal wellness profiling cohort

Tebani, A., A. Gummesson, W. Zhong, I. S. Koistinen, T. Lakshmikanth, L. M. Olsson, F. Boulund, M. Neiman, H. Stenlund, C. Hellstrom, M. J. Karlsson, M. Arif, T. Dodig-Crnkovic, A. Mardinoglu, S. Lee, C. Zhang, Y. Chen, A. Olin, J. Mikes, H. Danielsson, K. von Feilitzen, P. A. Jansson, O. Angeras, M. Huss, S. Kjellqvist, J. Odeberg, F. Edfors, V. Tremaroli, B. Forsstrom, J. M. Schwenk, P. Nilsson, T. Moritz, F. Backhed, L. Engstrand, P. Brodin, G. Bergstrom, M. Uhlen, and L. Fagerberg

Nat Commun, 11: 4487.

105) Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells

Zhan, C., G. Bidkhori, H. Schwarz, M. Malm, A. Mebrahtu, R. Field, C. Sellick, D. Hatton, P. Varley, A. Mardinoglu, J. Rockberg, and V. Chotteau

iScience, 23: 101653.

104) MEMOTE for standardized genome-scale metabolic model testing

Lieven, C., M. E. Beber, B. G. Olivier, F. T. Bergmann, M. Ataman, P. Babaei, J. A. Bartell, L. M. Blank, S. Chauhan, K. Correia, C. Diener, A. Drager, B. E. Ebert, J. N. Edirisinghe, J. P. Faria, A. M. Feist, G. Fengos, R. M. T. Fleming, B. Garcia-Jimenez, V. Hatzimanikatis, W. van Helvoirt, C. S. Henry, H. Hermjakob, M. J. Herrgard, A. Kaafarani, H. U. Kim, Z. King, S. Klamt, E. Klipp, J. J. Koehorst, M. Konig, M. Lakshmanan, D. Y. Lee, S. Y. Lee, S. Lee, N. E. Lewis, F. Liu, H. Ma, D. Machado, R. Mahadevan, P. Maia, A. Mardinoglu, G. L. Medlock, J. M. Monk, J. Nielsen, L. K. Nielsen, J. Nogales, I. Nookaew, B. O. Palsson, J. A. Papin, K. R. Patil, M. Poolman, N. D. Price, O. Resendis-Antonio, A. Richelle, I. Rocha, B. J. Sanchez, P. J. Schaap, R. S. Malik Sheriff, S. Shoaie, N. Sonnenschein, B. Teusink, P. Vilaca, J. O. Vik, J. A. H. Wodke, J. C. Xavier, Q. Yuan, M. Zakhartsev, and C. Zhang

Nat Biotechnol, 38: 272-76.

103) Neuroprotective effects of boron nitride nanoparticles in the experimental Parkinson’s disease model against MPP+ induced apoptosis

Kucukdogru, R., H. Turkez, M. E. Arslan, O. O. Tozlu, E. Sonmez, A. Mardinoglu, I. Cacciatore, and A. Di Stefano

Metab Brain Dis, 35: 947-57.

102) Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation

Pagoni, A., L. Marinelli, A. Di Stefano, M. Ciulla, H. Turkez, A. Mardinoglu, S. Vassiliou, and I. Cacciatore

Eur J Med Chem, 186: 111880.

101) Publisher Correction: MEMOTE for standardized genome-scale metabolic model testing

Lieven, C., M. E. Beber, B. G. Olivier, F. T. Bergmann, M. Ataman, P. Babaei, J. A. Bartell, L. M. Blank, S. Chauhan, K. Correia, C. Diener, A. Drager, B. E. Ebert, J. N. Edirisinghe, J. P. Faria, A. M. Feist, G. Fengos, R. M. T. Fleming, B. Garcia-Jimenez, V. Hatzimanikatis, W. van Helvoirt, C. S. Henry, H. Hermjakob, M. J. Herrgard, A. Kaafarani, H. U. Kim, Z. King, S. Klamt, E. Klipp, J. J. Koehorst, M. Konig, M. Lakshmanan, D. Y. Lee, S. Y. Lee, S. Lee, N. E. Lewis, F. Liu, H. Ma, D. Machado, R. Mahadevan, P. Maia, A. Mardinoglu, G. L. Medlock, J. M. Monk, J. Nielsen, L. K. Nielsen, J. Nogales, I. Nookaew, B. O. Palsson, J. A. Papin, K. R. Patil, M. Poolman, N. D. Price, O. Resendis-Antonio, A. Richelle, I. Rocha, B. J. Sanchez, P. J. Schaap, R. S. M. Sheriff, S. Shoaie, N. Sonnenschein, B. Teusink, P. Vilaca, J. O. Vik, J. A. H. Wodke, J. C. Xavier, Q. Yuan, M. Zakhartsev, and C. Zhang

Nat Biotechnol, 38: 504.

100) Skeletal Muscle Transcriptomic Comparison between Long-Term Trained and Untrained Men and Women

Chapman, M. A., M. Arif, E. B. Emanuelsson, S. M. Reitzner, M. E. Lindholm, A. Mardinoglu, and C. J. Sundberg

Cell Rep, 31: 107808.

99) Systems Biology Approaches to Understand the Host-Microbiome Interactions in Neurodegenerative Diseases

Rosario, D., J. Boren, M. Uhlen, G. Proctor, D. Aarsland, A. Mardinoglu, and S. Shoaie

Front Neurosci, 14: 716.

98) The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease

Zhang, C., E. Bjornson, M. Arif, A. Tebani, A. Lovric, R. Benfeitas, M. Ozcan, K. Juszczak, W. Kim, J. T. Kim, G. Bidkhori, M. Stahlman, P. O. Bergh, M. Adiels, H. Turkez, M. R. Taskinen, J. Bosley, H. U. Marschall, J. Nielsen, M. Uhlen, J. Boren, and A. Mardinoglu

Mol Syst Biol, 16: e9495.

97) The in vitro cytotoxic, genotoxic, and oxidative damage potentials of the oral artificial sweetener aspartame on cultured human blood cells

Cadirci, K., O. Ozdemir Tozlu, H. Turkez, and A. Mardinoglu

Turk J Med Sci, 50: 448-54.

96) A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

Uhlen, M., M. J. Karlsson, W. Zhong, A. Tebani, C. Pou, J. Mikes, T. Lakshmikanth, B. Forsstrom, F. Edfors, J. Odeberg, A. Mardinoglu, C. Zhang, K. von Feilitzen, J. Mulder, E. Sjostedt, A. Hober, P. Oksvold, M. Zwahlen, F. Ponten, C. Lindskog, A. Sivertsson, L. Fagerberg, and P. Brodin

Science, 366.

95) Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia

Klevstig, M., M. Arif, M. Mannila, S. Svedlund, I. Mardani, M. Stahlman, L. Andersson, M. Lindbom, A. Miljanovic, A. Franco-Cereceda, P. Eriksson, A. Jeppsson, L. M. Gan, M. Levin, A. Mardinoglu, E. Ehrenborg, and J. Boren

J Mol Cell Cardiol, 137: 1-8.

94) The human secretome

Uhlen, M., M. J. Karlsson, A. Hober, A. S. Svensson, J. Scheffel, D. Kotol, W. Zhong, A. Tebani, L. Strandberg, F. Edfors, E. Sjostedt, J. Mulder, A. Mardinoglu, A. Berling, S. Ekblad, M. Dannemeyer, S. Kanje, J. Rockberg, M. Lundqvist, M. Malm, A. L. Volk, P. Nilsson, A. Manberg, T. Dodig-Crnkovic, E. Pin, M. Zwahlen, P. Oksvold, K. von Feilitzen, R. S. Haussler, M. G. Hong, C. Lindskog, F. Ponten, B. Katona, J. Vuu, E. Lindstrom, J. Nielsen, J. Robinson, B. Ayoglu, D. Mahdessian, D. Sullivan, P. Thul, F. Danielsson, C. Stadler, E. Lundberg, G. Bergstrom, A. Gummesson, B. G. Voldborg, H. Tegel, S. Hober, B. Forsstrom, J. M. Schwenk, L. Fagerberg, and A. Sivertsson

Sci Signal, 12.

93) Systems biology perspective for studying the gut microbiota in human physiology and liver diseases

Altay, O., J. Nielsen, M. Uhlen, J. Boren, and A. Mardinoglu

EBioMedicine, 49: 364-73.

92) The Potential Use of Metabolic Cofactors in Treatment of NAFLD

Mardinoglu, A., D. Ural, M. Zeybel, H. H. Yuksel, M. Uhlen, and J. Boren

Nutrients, 11.

91) Multi-Omic Data Interpretation to Repurpose Subtype Specific Drug Candidates for Breast Cancer

Turanli, B., K. Karagoz, G. Bidkhori, R. Sinha, M. L. Gatza, M. Uhlen, A. Mardinoglu, and K. Y. Arga

Front Genet, 10: 420.

90) Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes

Harms, M. J., Q. Li, S. Lee, C. Zhang, B. Kull, S. Hallen, A. Thorell, I. Alexandersson, C. E. Hagberg, X. R. Peng, A. Mardinoglu, K. L. Spalding, and J. Boucher

Cell Rep, 27: 213-25 e5.

89) Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning

Turanli, B., C. Zhang, W. Kim, R. Benfeitas, M. Uhlen, K. Y. Arga, and A. Mardinoglu

EBioMedicine, 42: 386-96.

88) Expression of PD-L1 and PD-1 in Chemoradiotherapy-Naive Esophageal and Gastric Adenocarcinoma: Relationship With Mismatch Repair Status and Survival

Svensson, M. C., D. Borg, C. Zhang, C. Hedner, B. Nodin, M. Uhlen, A. Mardinoglu, K. Leandersson, and K. Jirstrom

Front Oncol, 9: 136.

87) Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function

Liu, Z., C. Zhang, S. Lee, W. Kim, M. Klevstig, A. M. Harzandi, N. Sikanic, M. Arif, M. Stahlman, J. Nielsen, M. Uhlen, J. Boren, and A. Mardinoglu

Metab Eng, 52: 263-72.

86) Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis

Benfeitas, R., G. Bidkhori, B. Mukhopadhyay, M. Klevstig, M. Arif, C. Zhang, S. Lee, R. Cinar, J. Nielsen, M. Uhlen, J. Boren, G. Kunos, and A. Mardinoglu

EBioMedicine, 40: 471-87.

85) Discovery of KIRREL as a biomarker for prognostic stratification of patients with thin melanoma

Lundgren, S., H. Fagerstrom-Vahman, C. Zhang, L. Ben-Dror, A. Mardinoglu, M. Uhlen, B. Nodin, and K. Jirstrom

Biomark Res, 7: 1.

84) Elucidating the Reprograming of Colorectal Cancer Metabolism Using Genome-Scale Metabolic Modeling

Zhang, C., M. Aldrees, M. Arif, X. Li, A. Mardinoglu, and M. A. Aziz

Front Oncol, 9: 681.

83) LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

Cadenas, C., S. Vosbeck, K. Edlund, K. Grgas, K. Madjar, B. Hellwig, A. Adawy, A. Glotzbach, J. D. Stewart, M. S. Lesjak, D. Franckenstein, M. Claus, H. Hayen, A. Schriewer, K. Gianmoena, S. Thaler, M. Schmidt, P. Micke, F. Ponten, A. Mardinoglu, C. Zhang, H. U. Kafferlein, C. Watzl, S. Frank, J. Rahnenfuhrer, R. Marchan, and J. G. Hengstler

Int J Cancer, 145: 901-15.

82) Plasma Proteomics Analysis Reveals Dysregulation of Complement Proteins and Inflammation in Acquired Obesity-A Study on Rare BMI-Discordant Monozygotic Twin Pairs

Sahebekhtiari, N., M. Saraswat, S. Joenvaara, R. Jokinen, A. Lovric, S. Kaye, A. Mardinoglu, A. Rissanen, J. Kaprio, R. Renkonen, and K. H. Pietilainen

Proteomics Clin Appl, 13: e1800173.

81) Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes

Bidkhori, G., R. Benfeitas, M. Klevstig, C. Zhang, J. Nielsen, M. Uhlen, J. Boren, and A. Mardinoglu

Proc Natl Acad Sci U S A, 115: E11874-E83.

80) Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice

Haversen, L., J. P. Sundelin, A. Mardinoglu, M. Rutberg, M. Stahlman, U. Wilhelmsson, L. M. Hulten, M. Pekny, P. Fogelstrand, J. F. Bentzon, M. Levin, and J. Boren

Sci Rep, 8: 16973.

79) A Network-Based Cancer Drug Discovery: From Integrated Multi-Omics Approaches to Precision Medicine

Turanli, B., K. Karagoz, G. Gulfidan, R. Sinha, A. Mardinoglu, and K. Y. Arga

Curr Pharm Des, 24: 3778-90.

78) Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome

Lovric, A., M. Graner, E. Bjornson, M. Arif, R. Benfeitas, K. Nyman, M. Stahlman, M. O. Pentikainen, J. Lundbom, A. Hakkarainen, R. Siren, M. S. Nieminen, N. Lundbom, K. Lauerma, M. R. Taskinen, A. Mardinoglu, and J. Boren

Sci Rep, 8: 14200.

77) Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia

Danielsson, F., E. Fasterius, D. Sullivan, L. Hases, K. Sanli, C. Zhang, A. Mardinoglu, C. Al-Khalili, M. Huss, M. Uhlen, C. Williams, and E. Lundberg

Oncotarget, 9: 19730-44.

76) Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents

Zhang, X., A. Mardinoglu, L. A. B. Joosten, J. A. Kuivenhoven, Y. Li, M. G. Netea, and A. K. Groen

Front Physiol, 9: 139.

75) ESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based Modeling

Zhang, C., G. Bidkhori, R. Benfeitas, S. Lee, M. Arif, M. Uhlen, and A. Mardinoglu

Front Physiol, 9: 1355.

74) Meta-Analysis of Adiponectin as a Biomarker for the Detection of Metabolic Syndrome

Liu, Z., S. Liang, S. Que, L. Zhou, S. Zheng, and A. Mardinoglu

Front Physiol, 9: 1238.

73) Metabolic Network-Based Identification and Prioritization of Anticancer Targets Based on Expression Data in Hepatocellular Carcinoma

Bidkhori, G., R. Benfeitas, E. Elmas, M. N. Kararoudi, M. Arif, M. Uhlen, J. Nielsen, and A. Mardinoglu

Front Physiol, 9: 916.

72) Drug Repositioning for Effective Prostate Cancer Treatment

Turanli, B., M. Grotli, J. Boren, J. Nielsen, M. Uhlen, K. Y. Arga, and A. Mardinoglu

Front Physiol, 9: 500.

71) Understanding the Representative Gut Microbiota Dysbiosis in Metformin-Treated Type 2 Diabetes Patients Using Genome-Scale Metabolic Modeling

Rosario, D., R. Benfeitas, G. Bidkhori, C. Zhang, M. Uhlen, S. Shoaie, and A. Mardinoglu

Front Physiol, 9: 775.

70) Systems biology in hepatology: approaches and applications

Mardinoglu, A., J. Boren, U. Smith, M. Uhlen, and J. Nielsen

Nat Rev Gastroenterol Hepatol, 15: 365-77.

69) Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma

Huvila, J., T. D. Laajala, P. H. Edqvist, A. Mardinoglu, L. Talve, F. Ponten, S. Grenman, O. Carpen, T. Aittokallio, and A. Auranen

Gynecol Oncol, 149: 173-80.

68) Associations of PD-1 and PD-L1 expression with mismatch repair status and prognosis in chemoradiotherapy-naïve esophageal and gastric adenocarcinoma.

Svensson M, Borg D, Zhang C, Hedner C, Nodin B, Uhlen M, Mardinoglu A, Leandersson K, Jirstrom K.

Journal of Clinical Oncology, no. 4_suppl 9-9.

67) An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans

Mardinoglu, A., H. Wu, E. Bjornson, C. Zhang, A. Hakkarainen, S. M. Rasanen, S. Lee, R. M. Mancina, M. Bergentall, K. H. Pietilainen, S. Soderlund, N. Matikainen, M. Stahlman, P. O. Bergh, M. Adiels, B. D. Piening, M. Graner, N. Lundbom, K. J. Williams, S. Romeo, J. Nielsen, M. Snyder, M. Uhlen, G. Bergstrom, R. Perkins, H. U. Marschall, F. Backhed, M. R. Taskinen, and J. Boren

Cell Metab, 27: 559-71 e5.

66) Broad Views of Non-alcoholic Fatty Liver Disease

Mardinoglu, A., M. Uhlen, and J. Boren

Cell Syst, 6(1):7-9.

65) Integrative Personal Omics Profiles during Periods of Weight Gain and Loss

Piening, B. D., W. Zhou, K. Contrepois, H. Rost, G. J. Gu Urban, T. Mishra, B. M. Hanson, E. J. Bautista, S. Leopold, C. Y. Yeh, D. Spakowicz, I. Banerjee, C. Chen, K. Kukurba, D. Perelman, C. Craig, E. Colbert, D. Salins, S. Rego, S. Lee, C. Zhang, J. Wheeler, M. R. Sailani, L. Liang, C. Abbott, M. Gerstein, A. Mardinoglu, U. Smith, D. L. Rubin, S. Pitteri, E. Sodergren, T. L. McLaughlin, G. M. Weinstock, and M. P. Snyder

Cell Syst, 6: 157-70 e8.

64) Dose-response analysis revealed closer relationship between obesity and perioperative outcomes in patients after liver transplantation

Liu, Z., A. Mardinoglu, and S. Que

Aliment Pharmacol Ther, 47: 310-12.

63) Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes

Mardinoglu, A., S. Gogg, L. A. Lotta, A. Stancakova, A. Nerstedt, J. Boren, M. Bluher, E. Ferrannini, C. Langenberg, N. J. Wareham, M. Laakso, and U. Smith

EBioMedicine, 27: 151-55.

62) Translational study reveals a two-faced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification

Karnevi, E., L. B. Dror, A. Mardinoglu, J. Elebro, M. Heby, S. E. Olofsson, B. Nodin, J. Eberhard, W. Gallagher, M. Uhlen, and K. Jirstrom

Oncotarget, 9: 6188-200.

61) TCSBN: a database of tissue and cancer specific biological networks

Lee, S., C. Zhang, M. Arif, Z. Liu, R. Benfeitas, G. Bidkhori, S. Deshmukh, M. Al Shobky, A. Lovric, J. Boren, J. Nielsen, M. Uhlen, and A. Mardinoglu

Nucleic Acids Res, 46: D595-D600.

60) High Cell Density Perfusion Culture has a Maintained Exoproteome and Metabolome

Zamani, L., M. Lundqvist, Y. Zhang, M. Aberg, F. Edfors, G. Bidkhori, A. Lindahl, A. Mie, A. Mardinoglu, R. Field, R. Turner, J. Rockberg, and V. Chotteau

Biotechnol J, 13: e1800036.

59) The effect of the TM6SF2 E167K variant on liver steatosis and fibrosis in patients with chronic hepatitis C: a meta-analysis

Liu, Z., S. Que, L. Zhou, S. Zheng, S. Romeo, A. Mardinoglu, and L. Valenti

Sci Rep, 7: 9273.

58) Network analyses identify liver-specific targets for treating liver diseases

Lee S, Zhang C, Liu Z, Klevstig M, Mukhopadhyay B, Bergentall M, Cinar R, Ståhlman M, Sikanic N, Park JK, Deshmukh S.

Molecular systems biology. 13(8):938.

57) A pathology atlas of the human cancer transcriptome

Uhlen M, Zhang C, Lee S, Sjöstedt E, Fagerberg L, Bidkhori G, Benfeitas R, Arif M, Liu Z, Edfors F, Sanli K

Science, 357(6352):eaan2507

56) Rediscussion on linearity between fibrosis stages and mortality risk in nonalcoholic fatty liver disease patients

Liu, Z., S. Que, and A. Mardinoglu

Hepatology, 66: 1357-58.

55) Selection of complementary foods based on optimal nutritional values

Sen P, Mardinogulu A, Nielsen J.

Sci Rep, 7(1):5413

54) Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease

Mardinoglu A, Stančáková A, Lotta LA, Kuusisto J, Boren J, Blueher M, Wareham NJ, Ferrannini E, Groop PH, Laakso M, Langenberg C.

Cell metabolism. 26(2):281-3.

53) Improving the economics of NASH/NAFLD treatment through the use of systems biology

Bosley, J., C. Boren, S. Lee, M. Grotli, J. Nielsen, M. Uhlen, J. Boren, and A. Mardinoglu

Drug Discov Today, 22: 1532-38.

52) New Challenges to Study Heterogeneity in Cancer Redox Metabolism

Benfeitas, R., M. Uhlen, J. Nielsen, and A. Mardinoglu

Front Cell Dev Biol, 5: 65.

51) A subcellular map of the human proteome

Thul, P. J., L. Akesson, M. Wiking, D. Mahdessian, A. Geladaki, H. Ait Blal, T. Alm, A. Asplund, L. Bjork, L. M. Breckels, A. Backstrom, F. Danielsson, L. Fagerberg, J. Fall, L. Gatto, C. Gnann, S. Hober, M. Hjelmare, F. Johansson, S. Lee, C. Lindskog, J. Mulder, C. M. Mulvey, P. Nilsson, P. Oksvold, J. Rockberg, R. Schutten, J. M. Schwenk, A. Sivertsson, E. Sjostedt, M. Skogs, C. Stadler, D. P. Sullivan, H. Tegel, C. Winsnes, C. Zhang, M. Zwahlen, A. Mardinoglu, F. Ponten, K. von Feilitzen, K. S. Lilley, M. Uhlen, and E. Lundberg

Science, 356(6340):eaal3321.

50) AUP1 (Ancient Ubiquitous Protein 1): A Molecular Link Between Hepatic Lipid Mobilization and VLDL Secretion

Mardinoglu, A., and J. Boren

Arterioscler Thromb Vasc Biol, 37: 609-10.

49) Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD

Mardinoglu A, Bjornson E, Zhang C, Klevstig M, Söderlund S, Ståhlman M, Adiels M, Hakkarainen A, Lundbom N, Kilicarslan M, Hallström BM.

Mol Syst Biol, 13(3):916.

48) Predicting growth of the healthy infant using a genome scale metabolic model

Nilsson, A., A. Mardinoglu, and J. Nielsen

NPJ Syst Biol Appl, 3: 3.

47) Principles of Systems Biology, No. 21

Cao J, Packer J, Waterston R, Trapnell C, Shendure J, Rajaram S, Wu LF, Altschuler SJ, Liang J, O’Brien LE, Eizenberg-Magar I.

Cell Systems. 5(3):158-60.

46) Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins

Heinonen, S., M. Muniandy, J. Buzkova, A. Mardinoglu, A. Rodriguez, G. Fruhbeck, A. Hakkarainen, J. Lundbom, N. Lundbom, J. Kaprio, A. Rissanen, and K. H. Pietilainen

Diabetologia, 60(1):169-181.

45) Adaptive Evolution of Phosphorus Metabolism in Prochlorococcus

Casey, J. R., A. Mardinoglu, J. Nielsen, and D. M. Karl

mSystems, 1.

44) ARAP2 promotes GLUT1-mediated basal glucose uptake through regulation of sphingolipid metabolism

Chaudhari, A., L. Haversen, R. Mobini, L. Andersson, M. Stahlman, E. Lu, M. Rutberg, P. Fogelstrand, K. Ekroos, A. Mardinoglu, M. Levin, R. Perkins, and J. Boren

Biochim Biophys Acta, 1861(11):1643-1651.

43) Liver: Phenotypic and genetic variance: a systems approach to the liver

Mardinoglu, A., and M. Uhlen

Nat Rev Gastroenterol Hepatol, 13(8):439-40.

42) Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance

Lee, S., C. Zhang, M. Kilicarslan, B. D. Piening, E. Bjornson, B. M. Hallstrom, A. K. Groen, E. Ferrannini, M. Laakso, M. Snyder, M. Bluher, M. Uhlen, J. Nielsen, U. Smith, M. J. Serlie, J. Boren, and A. Mardinoglu

Cell Metab, 24: 172-84.

41) Dysregulated signaling hubs of liver lipid metabolism reveal hepatocellular carcinoma pathogenesis

Lee, S., A. Mardinoglu, C. Zhang, D. Lee, and J. Nielsen

Nucleic Acids Res, 44: 5529-39.

40) Investigating the Combinatory Effects of Biological Networks on Gene Co-expression

Zhang, C., S. Lee, A. Mardinoglu, and Q. Hua

Front Physiol, 7: 160.

39) Transcriptomics resources of human tissues and organs

Uhlen, M., B. M. Hallstrom, C. Lindskog, A. Mardinoglu, F. Ponten, and J. Nielsen

Mol Syst Biol, 12: 862.

38) Confounding Effects of Metformin on the Human Gut Microbiome in Type 2 Diabetes

Mardinoglu, A., J. Boren, and U. Smith

Cell Metab, 23(1):10-2.

37) Editorial: The Impact of Systems Medicine on Human Health and Disease

Mardinoglu, A., and J. Nielsen

Front Physiol, 7: 552.

36) Systems biology analysis of hepatitis C virus infection reveals the role of copy number increases in regions of chromosome 1q in hepatocellular carcinoma metabolism

Elsemman, I. E., A. Mardinoglu, S. Shoaie, T. H. Soliman, and J. Nielsen

Mol Biosyst, 12: 1496-506.

35) Personalized Cardiovascular Disease Prediction and Treatment-A Review of Existing Strategies and Novel Systems Medicine Tools

Bjornson, E., J. Boren, and A. Mardinoglu

Front Physiol, 7: 2.

34) Stratification of hepatocellular carcinoma patients based on acetate utilization

Björnson E, Mukhopadhyay B, Asplund A, Pristovsek N, Cinar R, Romeo S, Uhlen M, Kunos G, Nielsen J, Mardinoglu A.

Cell reports. 13(9):2014-26.

33) The gut microbiota modulates host amino acid and glutathione metabolism in mice

Mardinoglu, A., S. Shoaie, M. Bergentall, P. Ghaffari, C. Zhang, E. Larsson, F. Backhed, and J. Nielsen

Mol Syst Biol, 11: 834.

32) New paradigms for metabolic modeling of human cells

Mardinoglu, A., and J. Nielsen

Curr Opin Biotechnol, 34: 91-7.

31) Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

Shoaie, S., P. Ghaffari, P. Kovatcheva-Datchary, A. Mardinoglu, P. Sen, E. Pujos-Guillot, T. de Wouters, C. Juste, S. Rizkalla, J. Chilloux, L. Hoyles, J. K. Nicholson, M. ICRO-Obes Consortium, J. Dore, M. E. Dumas, K. Clement, F. Backhed, and J. Nielsen

Cell Metab, 22: 320-31.

30) The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling

Lindskog, C., J. Linne, L. Fagerberg, B. M. Hallstrom, C. J. Sundberg, M. Lindholm, M. Huss, C. Kampf, H. Choi, D. A. Liem, P. Ping, L. Varemo, A. Mardinoglu, J. Nielsen, E. Larsson, F. Ponten, and M. Uhlen

BMC Genomics, 16: 475.

29) Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes

Varemo, L., C. Scheele, C. Broholm, A. Mardinoglu, C. Kampf, A. Asplund, I. Nookaew, M. Uhlen, B. K. Pedersen, and J. Nielsen

Cell Rep, 11: 921-33.

28) Logical transformation of genome-scale metabolic models for gene level applications and analysis

Zhang, C., B. Ji, A. Mardinoglu, J. Nielsen, and Q. Hua

Bioinformatics, 31: 2324-31.

27) Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling

Ghaffari, P., A. Mardinoglu, A. Asplund, S. Shoaie, C. Kampf, M. Uhlen, and J. Nielsen

Sci Rep, 5: 8183.

26) Tissue-based map of the human proteome

Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Sivertsson Å, Kampf C, Sjöstedt E, Asplund A, Olsson I.

Science, 347(6220):1260419.

25) Cancer Metabolism: A Modeling Perspective

Ghaffari, P., A. Mardinoglu, and J. Nielsen

Front Physiol, 6: 382.

24) Kinetic Studies to Elucidate Impaired Metabolism of Triglyceride-rich Lipoproteins in Humans

Adiels, M., A. Mardinoglu, M. R. Taskinen, and J. Boren

Front Physiol, 6: 342.

23) Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue

Mardinoglu, A., J. T. Heiker, D. Gartner, E. Bjornson, M. R. Schon, G. Flehmig, N. Kloting, K. Krohn, M. Fasshauer, M. Stumvoll, J. Nielsen, and M. Bluher

Sci Rep, 5: 14841.

22) Modelling the effect of SPION size in a stent assisted magnetic drug targeting system with interparticle interactions

Mardinoglu, A., and P. J. Cregg

ScientificWorldJournal, 2015: 618658.

21) Proteomics. Tissue-based map of the human proteome

Uhlen, M., L. Fagerberg, B. M. Hallstrom, C. Lindskog, P. Oksvold, A. Mardinoglu, A. Sivertsson, C. Kampf, E. Sjostedt, A. Asplund, I. Olsson, K. Edlund, E. Lundberg, S. Navani, C. A. Szigyarto, J. Odeberg, D. Djureinovic, J. O. Takanen, S. Hober, T. Alm, P. H. Edqvist, H. Berling, H. Tegel, J. Mulder, J. Rockberg, P. Nilsson, J. M. Schwenk, M. Hamsten, K. von Feilitzen, M. Forsberg, L. Persson, F. Johansson, M. Zwahlen, G. von Heijne, J. Nielsen, and F. Ponten

Science, 347: 1260419.

20) Toxicogenomics directory of chemically exposed human hepatocytes

Grinberg, M., R. M. Stober, K. Edlund, E. Rempel, P. Godoy, R. Reif, A. Widera, K. Madjar, W. Schmidt-Heck, R. Marchan, A. Sachinidis, D. Spitkovsky, J. Hescheler, H. Carmo, M. D. Arbo, B. van de Water, S. Wink, M. Vinken, V. Rogiers, S. Escher, B. Hardy, D. Mitic, G. Myatt, T. Waldmann, A. Mardinoglu, G. Damm, D. Seehofer, A. Nussler, T. S. Weiss, A. Oberemm, A. Lampen, M. M. Schaap, M. Luijten, H. van Steeg, W. E. Thasler, J. C. Kleinjans, R. H. Stierum, M. Leist, J. Rahnenfuhrer, and J. G. Hengstler

Arch Toxicol, 88: 2261-87.

19) Defining the human adipose tissue proteome to reveal metabolic alterations in obesity

Mardinoglu, A., C. Kampf, A. Asplund, L. Fagerberg, B. M. Hallstrom, K. Edlund, M. Bluher, F. Ponten, M. Uhlen, and J. Nielsen

J Proteome Res, 13: 5106-19.

18) Defining the human gallbladder proteome by transcriptomics and affinity proteomics

Kampf, C., A. Mardinoglu, L. Fagerberg, B. M. Hallstrom, A. Danielsson, J. Nielsen, F. Ponten, and M. Uhlen

Proteomics, 14: 2498-507.

17) The human liver-specific proteome defined by transcriptomics and antibody-based profiling

Kampf, C., A. Mardinoglu, L. Fagerberg, B. M. Hallstrom, K. Edlund, E. Lundberg, F. Ponten, J. Nielsen, and M. Uhlen

FASEB J, 28: 2901-14.

16) Identification of anticancer drugs for hepatocellular carcinoma through personalized genome-scale metabolic modeling

Agren, R., A. Mardinoglu, A. Asplund, C. Kampf, M. Uhlen, and J. Nielsen

Mol Syst Biol, 10: 721.

15) Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

Fagerberg, L., B. M. Hallstrom, P. Oksvold, C. Kampf, D. Djureinovic, J. Odeberg, M. Habuka, S. Tahmasebpoor, A. Danielsson, K. Edlund, A. Asplund, E. Sjostedt, E. Lundberg, C. A. Szigyarto, M. Skogs, J. O. Takanen, H. Berling, H. Tegel, J. Mulder, P. Nilsson, J. M. Schwenk, C. Lindskog, F. Danielsson, A. Mardinoglu, A. Sivertsson, K. von Feilitzen, M. Forsberg, M. Zwahlen, I. Olsson, S. Navani, M. Huss, J. Nielsen, F. Ponten, and M. Uhlen

Mol Cell Proteomics, 13: 397-406.

14) Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease

Mardinoglu, A., R. Agren, C. Kampf, A. Asplund, M. Uhlen, and J. Nielsen

Nat Commun, 5: 3083.

13) Genome‐scale modeling of human metabolism–a systems biology approach

Mardinoglu A, Gatto F, Nielsen J.

Biotechnology journal. 8(9):985-96.

12) Understanding the interactions between bacteria in the human gut through metabolic modeling

Shoaie, S., F. Karlsson, A. Mardinoglu, I. Nookaew, S. Bordel, and J. Nielsen

Sci Rep, 3: 2532.

11) Integration of clinical data with a genome‐scale metabolic model of the human adipocyte

Mardinoglu A, Agren R, Kampf C, Asplund A, Nookaew I, Jacobson P, Walley AJ, Froguel P, Carlsson LM, Uhlen M, Nielsen J.

Mol Syst Biol (2013)9:649

10) Genome-scale modeling of human metabolism – a systems biology approach

Mardinoglu, A., F. Gatto, and J. Nielsen

Biotechnol J, 8: 985-96.

9) Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT

Agren, R., S. Bordel, A. Mardinoglu, N. Pornputtapong, I. Nookaew, and J. Nielsen

PLoS Comput Biol, 8: e1002518.

8) Systems medicine and metabolic modelling

Mardinoglu, A., and J. Nielsen

J Intern Med, 271: 142-54.

7) Inclusion of interactions in mathematical modelling of implant assisted magnetic drug targeting

Cregg PJ, Murphy K, Mardinoglu A.

Applied Mathematical Modelling. 36(1):1-34.

6) Development of artificial neuronal networks for molecular communication

Balasubramaniam S, Boyle NT, Della-Chiesa A, Walsh F, Mardinoglu A, Botvich D, Prina-Mello A.

Nano Communication Networks. 2(2-3):150-60.

5) Artificial backbone neuronal network for nano scale sensors

F. Walsh, N.T. Boyle, A. Mardinoglu, A. Della Chiesa, D. Botvich, A. Prina-Mello, S. Balasubramaniam

2011 IEEE Conference on Computer Communications Workshops (INFOCOM WKSHPS) (pp. 449-454). IEEE.

4) Theoretical modelling of physiologically stretched vessel in magnetisable stent assisted magnetic drug targetingapplication

Mardinoglu A, Cregg PJ, Murphy K, Curtin M, Prina-Mello A.

Journal of Magnetism and Magnetic Materials. 323(3-4):324-9.

3) Many particle magnetic dipole–dipole and hydrodynamic interactions in magnetizable stent assisted magnetic drug targeting

Cregg PJ, Murphy K, Mardinoglu A, Prina-Mello A.

Journal of Magnetism and Magnetic Materials. 322(15):2087-94.

2) Inclusion of magnetic dipole–dipole and hydrodynamic interactions in implant-assisted magnetic drug targeting

Cregg PJ, Murphy K, Mardinoglu A.

Journal of Magnetism and Magnetic Materials. 321(23):3893-8.

1) Calculation of nanoparticle capture efficiency in magnetic drug targeting

Cregg PJ, Murphy K, Mardinoglu A.

Journal of Magnetism and Magnetic Materials 320, no. 23: 3272-3275.